Available research opportunities within the program
Computational Biology
- Aladin Boriek - Respiratory muscle mechanics; computational models of tissue mechanics, mechanical role of structural proteins in skeletal and smooth muscles, mechanical signal transduction in skeletal and smooth muscles
- Jim Briggs - Computer-aided drug design; Molecular modeling; Computational biophysics
- Wah Chiu - Structural and Computational Biology of Biological Machines
- John W. Clark, Jr. - Cell Modeling; Engineering in Critical Care Medicine
- Cecilia Clementi - Theory of Protein Folding; Protein Modeling and Simulations; Folding/Function relationship
- Mauro Ferrari - Nanotechnology in Biomedical Applications
- George E. Fox - RNA structure, function & evolution; bioinformatics
- Dan Graur -
- Vincent J. Hilser - Experimental and theoretical studies of protein structure and dynamics.
- Lennart Johnsson - Computational Science
- Lydia E. Kavraki - Computation of Shape and Motion in Biology, Computer-Assisted Drug Design
- Olivier Lichtarge - Annotation and Designed Perturbation of Protein Function and Pathways
- Steve Ludtke - cryo-electron microscopy and single particle reconstruction
- Michael A. Mancini - Transcriptional analyses at the single cell level
- Aleksandar Milosavljevic - Bioinformatics and Comparative Genomics
- Read Montague - Computational Neuroscience, Neuroimaging, Neural economics
- Luay Nakhleh - Computational biology and bioinformatics
- Monte Pettitt - Theoretical and computational biology and biochemistry
- B. V. Venkataram Prasad - Structural Basis of replication in RNA viruses
- Peter Saggau - Mechanisms and Modulation of Synaptic Transmission; Single Neuron Computation; Advanced Optical Imaging Techniques in Neuroscience
- Michael F. Schmid - Image Processing and Electron Crystallography of Macromolecular Machines
- Gadi Shaulsky - Genetics and Functional Genomics of Dictyostelium Development
- George Weinstock - Genomics and molecular genetics applied to humans, microbial pathogens, and other microbial and mammalian organisms
- Theodore Wensel - Structure and Dynamics of Signal Transducing Membranes
- Lynn Zechiedrich - DNA topoisomererases and antimicrobial resistance
Top
Structural Biology
- Jim Briggs - Computer-aided drug design; Molecular modeling; Computational biophysics
- William Brownell - Cochlear biophysics and the mechanism of outer hair cell electromotility.
- Xiaomin Chen - Structural and Biochemical Studies of the Jak-STAT Signaling Pathway
- Wah Chiu - Structural and Computational Biology of Biological Machines
- Cecilia Clementi - Theory of Protein Folding; Protein Modeling and Simulations; Folding/Function relationship
- Henry Epstein, M.D. - Structural biology of myosin filaments, molecular chaperones, and protein kinase complexes.
- Mary Estes - Molecular biology and structure of virus assembly.
- George E. Fox - RNA structure, function & evolution; bioinformatics
- Hiram F Gilbert - Protein folding and catalysis of disulfide formation during protein secretion in yeast
- Susan Hamilton - Calcium Release Channel Structure and Function
- Vincent J. Hilser - Experimental and theoretical studies of protein structure and dynamics.
- Ray Jacobson - Biochemical and 3-Dimensional Structure Analysis of Basal Transcription Proteins/Complexes
- Olivier Lichtarge - Annotation and Designed Perturbation of Protein Function and Pathways
- Steve Ludtke - cryo-electron microscopy and single particle reconstruction
- Jianpeng Ma - Computational Molecular Biophysics and Structural Biology
- Pawel A. Penczek - Structural Determinatin of Proteins and Molecular Assemblies
- Monte Pettitt - Theoretical and computational biology and biochemistry
- James Pflugrath - New methods of macromolecular crystal data collection and structure determination
- Henry Pownall - Structures of Native and Model Plasma Lipoproteins
- B. V. Venkataram Prasad - Structural Basis of replication in RNA viruses
- Florante A. Quiocho - Protein Atomic Structure, Molecular Recognition and Function
- Michael F. Schmid - Image Processing and Electron Crystallography of Macromolecular Machines
- John Spudich - Photosensory Receptors & Signal Transduction / Microbial Rhodopsins
- Francis Tsai - Structure and Function of Macromolecular Complexes and Supramolecular Assemblies
- Theodore Wensel - Structure and Dynamics of Signal Transducing Membranes
- Pernilla Wittung-Stafshede - Biophysical characterization of protein-folding reactions, with emphasis on cofactor-binding proteins and proteins that require oligomeric assembly
- Lynn Zechiedrich - DNA topoisomererases and antimicrobial resistance
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Genomics
- George E. Fox - RNA structure, function & evolution; bioinformatics
- Richard Gibbs - The Human Genome Project; molecular basis of human genetic diseases; molecular evolution.
- Marek Kimmel - Informatics and statistical modeling of genome dynamics
- Ching C. Lau - Genomics and proteomics of cancer, bioinformatics, and development of targeted therapy.
- Olivier Lichtarge - Annotation and Designed Perturbation of Protein Function and Pathways
- Aleksandar Milosavljevic - Bioinformatics and Comparative Genomics
- Joel Morrisett - Imaging, Genomics, and Proteomics of Human Atherosclerosis
- Gadi Shaulsky - Genetics and Functional Genomics of Dictyostelium Development
- John Spudich - Photosensory Receptors & Signal Transduction / Microbial Rhodopsins
- George Weinstock - Genomics and molecular genetics applied to humans, microbial pathogens, and other microbial and mammalian organisms
- Lynn Zechiedrich - DNA topoisomererases and antimicrobial resistance
Top
Biophysics
- Aladin Boriek - Respiratory muscle mechanics; computational models of tissue mechanics, mechanical role of structural proteins in skeletal and smooth muscles, mechanical signal transduction in skeletal and smooth muscles
- Jim Briggs - Computer-aided drug design; Molecular modeling; Computational biophysics
- William Brownell - Cochlear biophysics and the mechanism of outer hair cell electromotility.
- Xiaomin Chen - Structural and Biochemical Studies of the Jak-STAT Signaling Pathway
- Wah Chiu - Structural and Computational Biology of Biological Machines
- John W. Clark, Jr. - Cell Modeling; Engineering in Critical Care Medicine
- Cecilia Clementi - Theory of Protein Folding; Protein Modeling and Simulations; Folding/Function relationship
- Anne Delcour - Molecular mechanisms of bacterial ion channels
- Henry Epstein, M.D. - Structural biology of myosin filaments, molecular chaperones, and protein kinase complexes.
- Hiram F Gilbert - Protein folding and catalysis of disulfide formation during protein secretion in yeast
- Susan Hamilton - Calcium Release Channel Structure and Function
- Vincent J. Hilser - Experimental and theoretical studies of protein structure and dynamics.
- Ray Jacobson - Biochemical and 3-Dimensional Structure Analysis of Basal Transcription Proteins/Complexes
- Ching-Hwa Kiang - Single-Molecule Force Spectroscopy of Biomolecules
- Olivier Lichtarge - Annotation and Designed Perturbation of Protein Function and Pathways
- Steve Ludtke - cryo-electron microscopy and single particle reconstruction
- Jianpeng Ma - Computational Molecular Biophysics and Structural Biology
- Michael A. Mancini - Transcriptional analyses at the single cell level
- Read Montague - Computational Neuroscience, Neuroimaging, Neural economics
- Joel Morrisett - Imaging, Genomics, and Proteomics of Human Atherosclerosis
- Steen Pedersen - Allosteric mechanisms of ion channel function
- Monte Pettitt - Theoretical and computational biology and biochemistry
- Paul Pfaffinger - Molecular Biology and Biophysics of Potassium Ion Channels
- Henry Pownall - Structures of Native and Model Plasma Lipoproteins
- B. V. Venkataram Prasad - Structural Basis of replication in RNA viruses
- Peter Saggau - Mechanisms and Modulation of Synaptic Transmission; Single Neuron Computation; Advanced Optical Imaging Techniques in Neuroscience
- Michael F. Schmid - Image Processing and Electron Crystallography of Macromolecular Machines
- John Spudich - Photosensory Receptors & Signal Transduction / Microbial Rhodopsins
- Francis Tsai - Structure and Function of Macromolecular Complexes and Supramolecular Assemblies
- Theodore Wensel - Structure and Dynamics of Signal Transducing Membranes
- Pernilla Wittung-Stafshede - Biophysical characterization of protein-folding reactions, with emphasis on cofactor-binding proteins and proteins that require oligomeric assembly
- Sam Wu - Retinal Neurophysiology
- Lynn Zechiedrich - DNA topoisomererases and antimicrobial resistance
Top
Proteomics
- Wah Chiu - Structural and Computational Biology of Biological Machines
- Mauro Ferrari - Nanotechnology in Biomedical Applications
- Hiram F Gilbert - Protein folding and catalysis of disulfide formation during protein secretion in yeast
- Ching C. Lau - Genomics and proteomics of cancer, bioinformatics, and development of targeted therapy.
- Olivier Lichtarge - Annotation and Designed Perturbation of Protein Function and Pathways
- Michael A. Mancini - Transcriptional analyses at the single cell level
- Joel Morrisett - Imaging, Genomics, and Proteomics of Human Atherosclerosis
- Timothy Palzkill - Molecular Basis of Antibiotic Resistance, Functional Genomics of Bacterial Pathogens
- B. V. Venkataram Prasad - Structural Basis of replication in RNA viruses
- Jun Qin - Network analysis proteomics; the human DNA damage signaling network
- Francis Tsai - Structure and Function of Macromolecular Complexes and Supramolecular Assemblies
- Theodore Wensel - Structure and Dynamics of Signal Transducing Membranes
- Lynn Zechiedrich - DNA topoisomererases and antimicrobial resistance
Top
Bioengineering
- Aladin Boriek - Respiratory muscle mechanics; computational models of tissue mechanics, mechanical role of structural proteins in skeletal and smooth muscles, mechanical signal transduction in skeletal and smooth muscles
- William Brownell - Cochlear biophysics and the mechanism of outer hair cell electromotility.
- John W. Clark, Jr. - Cell Modeling; Engineering in Critical Care Medicine
- Cecilia Clementi - Theory of Protein Folding; Protein Modeling and Simulations; Folding/Function relationship
- Anne Delcour - Molecular mechanisms of bacterial ion channels
- Mary E. Dickinson, Ph.D. - In vivo optical microscopy; Analysis of vascular networks; Role of mechanical forces in vertebrate development
- Mauro Ferrari - Nanotechnology in Biomedical Applications
- George E. Fox - RNA structure, function & evolution; bioinformatics
- Lydia E. Kavraki - Computation of Shape and Motion in Biology, Computer-Assisted Drug Design
- Olivier Lichtarge - Annotation and Designed Perturbation of Protein Function and Pathways
- Jianpeng Ma - Computational Molecular Biophysics and Structural Biology
- Peter Saggau - Mechanisms and Modulation of Synaptic Transmission; Single Neuron Computation; Advanced Optical Imaging Techniques in Neuroscience
Top
Neuroscience
- Hugo Bellen - Genetic and molecular analysis of neurotransmitter release and nervous system development in Drosophila
- William Brownell - Cochlear biophysics and the mechanism of outer hair cell electromotility.
- John W. Clark, Jr. - Cell Modeling; Engineering in Critical Care Medicine
- John A. Dani - In Vivo, Cellular, and Molecular Studies of Synaptic Communication and of Circuits Underlying Reward and Behavior
- Henry Epstein, M.D. - Structural biology of myosin filaments, molecular chaperones, and protein kinase complexes.
- Fabrizio Gabbiani - Biophysics of information processing in the nervous system
- Read Montague - Computational Neuroscience, Neuroimaging, Neural economics
- Steen Pedersen - Allosteric mechanisms of ion channel function
- Paul Pfaffinger - Molecular Biology and Biophysics of Potassium Ion Channels
- Peter Saggau - Mechanisms and Modulation of Synaptic Transmission; Single Neuron Computation; Advanced Optical Imaging Techniques in Neuroscience
- Theodore Wensel - Structure and Dynamics of Signal Transducing Membranes
- John Wilson - Basis for instability of trinucleotide repeats, oligonucleotide-based therapy for diseases of the eye
- Sam Wu - Retinal Neurophysiology
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