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Education
B.S. Biochemistry and Moledular Biology, Purdue University(1996)
Ph.D. Structural and Computational and Molecular Biophysics (2002)
Mathew Baker
Mathew Baker, Ph.D.
 Department: W.M. Keck Center for Compuational Biology Postdoctoral Fellow, Baylor College of Medicine (2002)
Address: 5008 Mimosa
Bellaire, TX 77401
Phone: 713-798-6989
Fax: 713-798-1625
Email: mbaker@bcm.tmc.edu
Web: ncmi.bcm.tmc.edu/~baker
Honors
Research Topic

Development and Applications of Intermediate Resolution Structural Analysis Tools: Integrating Bioinformatics and Electron Cryomicroscopy
Research Description
Selected Publications
  • Lu, G.Y., Zhou, Z.H., Baker, M.L., Jakana, J., Cai, D.Y., Wei, X.C., Chen, S.X., Gu, X.C., Chiu, W. (1998) Structure of the Double-Shelled Rice Dwarf Virus. J Virol (72), p 8541-8549.
  • Petrosino, J., Baker, M.L., Palzkill, T. (1999) Tolerance of Amino Acid Substitutions at Beta-Lactamase Core Positions as Determined by Site Directed Mutagenesis. Protein Eng (9), p 761-769.
  • Jiang, W.*, Baker M.L.*, Ludtke, S.J., Chiu, W. (2001) Bridging the Information Gap: Computational Tools for Intermediate Resolution Structure Interpretation. J Mol Biol (308), p 1033-1044. *contributed equally
  • Zhou, Z.H., Baker, M.L., Jiang, W., Dougherty, M., Jakana, J., Dong, G., Lu, G., Chiu, W. (2001) Protein Folds of the Rice Dwarf Virus Revealed by Electron Cryomicroscopy. Nat Struct Biol (8), p 868-873.
  • Jiang, W., Li, Z., Zhang, Z., Booth, C. R., Baker, M. L., Chiu, W. (2001) Semi-Automated Icosahedral Particle Reconstruction at Sub-nanometer Resolution. J Struct Biol (3), p214-225.
  • Chiu, W., Baker, M.L., Jiang, W., Zhou, Z.H. (2002) Deriving the Folds of Macromolecular Complexes Through Electron Cryomicroscopy and Bioinformatics Approaches. Curr Opin Struct Biol (2), p 263-269.
  • Baker, M.L., Serysheva, I.I., Sencer, S., Ludtke, S.J., Jiang, W., Chiu, W., Hamilton, S.L. (Accepted) The Skeletal Muscle Ca2+ Release Channel has an Oxidoreductase-like Domain.
  • Bowman, B.R., Baker, M.L., Rixon, F, Chiu. W., Quiocho, F. (Submitted) X-ray Structure of the Upper Domain of the Herpes Simplex Virus-1 Major Capsid Protein: Identification of a Novel Fold and its Functional Implications.
  • Baker, M.L., Jiang, W., Zhou, Z.H., Rixon, F., Chiu, W. (manuscript in preparation) Architecture of the Herpes Simplex Virus Major Capsid Protein Derived from Electron Cryomicroscopy and Bioinformatics
  • Jiang, W., Li, Z., Zhang, Z., Baker, M.L., Prevelige, P.E., Chiu, W. (manuscript in preparation) Structural Transformations of Bacteriophage P22 Seen at Sub-nanometer Resolutions.
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Last edited on: June 01, 2005

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