Login for Content Change Forget Your Password?
Education
B.S. in Biology, Fudan University, China (2005)
Mentor: George Weinstock
Lei Chen
Lei Chen
Baylor College of Medicine
Department: SCBMB
Address: Baylor College of Medicine
One Baylor Plaza
Houston, TX 77030

Currently as remote student at
Washington University Genome Sequecing Center
4444 Forest Park Ave
St. Louis, MO 63110
Phone:
Fax:
Email: lc1@bcm.edu
Web: genome.wustl.edu
Honors

Marc Dresden Excellence in Graduate Education Award (2006)
Research Topic

Computational Genomics
Research Description
 I have been working on genomic sequence assembly and related analysis. I assembled the low coverage dolphin genome and wallaby genome; analyzed the polymorphisms in several microbial genome as well as Dr. Watson's genome. Currently I am working on the meta-genomics aspect of the Human Microbiome Project. In detail, the project will study the symbiotic microbes within certain human organ as a whole, especially the ensemble of their genomes. We will be dealing with DNA sequence fragments from multiple microbes at differing abundunce together, possibly produced by different sequencing technologies. We do not only want to assemble them into longer more contiguous sequence, we want to set the standard to measure the diversity and other ensemble characteristics of the data, and develop methods to compare different individuals' metagenomics data directly. It could turn out that one's microbiome is equally important as one's genome in terms of disease diagnosis.
Selected Publications
  • DA Wheeler et al. The complete genome of an individual by massively parallel DNA sequencing. Nature. 2008 Apr 17;452(7189):872-6.

Last edited on: April 27, 2008

BCM Home |  BCM Intranet |  Contact BCM |  BCM Site Map |  Privacy Notices | Copy Rights @1998-2005 Baylor College of Medicine
Contact Us |  Login for Content Change
SCBMB, Room N204T, One Baylor Plaza, MS: BCM215, Houston, TX 77030
Phone: (713) 798-5197 Fax: (713) 798-6325
last modified, Apr. 27,  2008