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Education
B.S. Neurobiology, University of Texas at Dallas (2001)
Ph.D. Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine (2007)
David Mittelman
David Mittelman
Baylor College of Medicine
Department: Biochemistry
Address: One Baylor Plaza, BCM125
Houston, TX 77030
Phone: 713-798-3569
Fax: 713-798-6325
Email: David.Mittelman@bcm.edu
Web:
Honors

1997 - Research Grant Recipient, RISE Foundation
1998 - Academic Excellence Scholarship Recipient, University of Texas at Dallas
2003 - NEI T32 Training Grant Recipient
Research Topic

evolution and dna repair
Research Description
I am interested in the genetic pathways that induce genome variation and the role of these processes in evolution. For a list of most recent publications, search David Mittelman at PubMed.
Selected Publications

  • D.H. Morgan, D.M. Kristensen, D. Mittelman, O. Lichtarge (2006) ET Viewer: An Application for Predicting and Visualizing Functional Sites in Protein Structures. Bioinformatics, 22(16):2049-50.
  • V. Gorbunova, A. Seluanov, D. Mittelman, and J.H. Wilson (2004) Demethylation of the genome strongly destabilizes CAG/CTG trinucleotide repeats in mammalian cells. Hum. Mol. Genet., 13(23):2979-2989.
  • A. Seluanov, D. Mittelman, O.M. Pereira-Smith, J.H. Wilson, and V. Gorbunova (2004) DNA end joining becomes less efficient and more error-prone during cellular senescence. Proc. Natl. Acad. Sci. USA, 101(20):7624-9.
  • D. Mittelman, R. Sadreyev, and N. Grishin (2003) Probabilistic scoring measures for profile-profile comparison yield more accurate short seed alignments. Bioinformatics, 19(12):1531-1539.
  • R.P. Balog, Y. Ponce de Souza, H. Tang, G. DeMasellis, B. Gao, A. Avila, D. Gaban, D. Mittelman, J.D. Minna, K.J. Luebke, and H.R. Garner (2002) Parallel assessment of CpG methylation by two-color hybridization with oligonucleotide arrays. Analytical Biochemistry, 309(2):301-310.
  • K.J. Luebke, R.P. Balog, D. Mittelman and H.R. Garner (2002) Digital Optical Chemistry: A Novel System for the Rapid Fabrication of Custom Oligonucleotide Arrays, a chapter in Microfabricated Sensors, Application of Optical Technology for DNA Analysis, Usmani and Wai Tak Law, editors, American Chemical Society Publications.
  • A. Kulkarni, N. Williams, Y. Lian, J.D. Wren, D. Mittelman, A. Pertsemlidis, and H.R. Garner (2002) ARROGANT: an application to manipulate large gene collections. Bioinformatics, 18(11):1410-1417.
  • J.D. Wren, D. Mittelman, and H.R. Garner (2002) SIGNAL - Sequence Information and Genomic Analysis. Computer Methods and Programs in Biomedicine, 68(2):177-181.
  • A. Pertsemlidis, B. Miller, A. Pande, D. Mittelman, P. Schilling, M. Wei, M. Lerman, J. Minna, and H. Garner (2000) PANORAMA - An Integrated Web-Based Sequence Analysis Tool and Its Role in Gene Discovery. Genomics, 70(3): 300-306.

Last edited on: March 24, 2008


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